Percutaneous coronary stent implantation in children and young infants following surgical repair of congenital heart disease.

IF 2.1 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Cardiovascular diagnosis and therapy Pub Date : 2023-08-31 DOI:10.21037/cdt-23-54
Jameel A Al-Ata, Gaser A Abdelmohsen, Saud A Bahaidarah, Naif A Alkhushi, Mohamed H Abdelsalam, Samia B Bekheet, Osman O Al-Radi, Ahmed A Jamjoom, Ahmed F Elmahrouk, Abdulaziz J Alata, Aly A Yousef, Ahmed M Dohain
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Abstract

Background: Coronary artery stent implantation (CSI) in the pediatric population is rare. Only a few reports were published on managing postoperative coronary artery obstruction using coronary stents following surgical repair of congenital heart diseases (CHD). This study aimed to analyze the feasibility, indications, procedural technique, risk factors, and short-term outcomes of CSI after pediatric cardiac surgery.

Methods: In this retrospective cohort study, we reviewed all pediatric patients who underwent surgical repair of CHD requiring postoperative CSI in two cardiac centers (King Abdulaziz University Hospital and King Faisal Specialist Hospital and Research Center) between 2012 and 2022. Survival to hospital discharge was the study's primary outcome. The secondary outcomes included procedural success, duration of mechanical ventilation, intensive care unit (ICU) stay, hospital stay, need for coronary reintervention, and late mortality. A descriptive analysis was performed for the collected data from the patients' medical records.

Results: Eleven patients who underwent postoperative CSI were identified. The most common anatomic diagnosis was congenital aortic valve stenosis. All patients underwent cardiac catheterization on extracorporeal membrane oxygenation support except one patient, who presented with chest pain after cardiac surgery. Procedural success was achieved in all patients with excellent revascularization documented by post-procedural angiograms. Both patients who had late coronary events after cardiac surgery survived hospital discharge. There was no in-hospital mortality among the two patients who required stenting of only the right coronary artery. The four patients who required more than 120 minutes to complete the procedure had early mortality. After CSI, the median duration of mechanical ventilation and ICU stay was 12 and 17 days, respectively. Six patients (54.5%) survived hospital discharge post-CSI; they did not require re-intervention during the follow-up period (38-1,695 days).

Conclusions: CSI in pediatric patients can be performed with excellent procedural success for treating coronary artery stenosis after cardiac surgery. It could be considered a potential treatment strategy for this population.

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经皮冠状动脉支架植入术在儿童和婴儿先天性心脏病手术修复后的应用。
背景:冠状动脉支架植入术(CSI)在儿童人群中是罕见的。关于先天性心脏病(CHD)手术修复后使用冠状动脉支架治疗术后冠状动脉阻塞的报道很少。本研究旨在分析小儿心脏手术后CSI的可行性、适应证、手术技术、危险因素及短期预后。方法:在这项回顾性队列研究中,我们回顾了2012年至2022年间在两个心脏中心(阿卜杜勒阿齐兹国王大学医院和费萨尔国王专科医院和研究中心)接受手术修复冠心病需要术后CSI的所有儿科患者。存活至出院是该研究的主要结果。次要结局包括手术成功、机械通气时间、重症监护病房(ICU)停留时间、住院时间、冠状动脉再介入治疗需求和晚期死亡率。对从患者病历中收集的数据进行描述性分析。结果:11例患者接受了术后CSI。最常见的解剖诊断是先天性主动脉瓣狭窄。除1例患者在心脏手术后出现胸痛外,所有患者均在体外膜氧合支持下行心导管插入术。术后血管造影显示,所有患者血运重建良好,手术成功。心脏手术后发生晚期冠状动脉事件的两例患者均存活出院。两名只需要右冠状动脉支架植入术的患者中没有住院死亡率。需要超过120分钟完成手术的4名患者有早期死亡。CSI术后机械通气时间中位数为12天,ICU住院时间中位数为17天。6例(54.5%)患者在csi后存活出院;在随访期间(38- 1695天),他们不需要再次干预。结论:在小儿心脏手术后冠状动脉狭窄的治疗中,CSI具有良好的手术成功率。它可以被认为是这一人群的潜在治疗策略。
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来源期刊
Cardiovascular diagnosis and therapy
Cardiovascular diagnosis and therapy Medicine-Cardiology and Cardiovascular Medicine
CiteScore
4.90
自引率
4.20%
发文量
45
期刊介绍: The journal ''Cardiovascular Diagnosis and Therapy'' (Print ISSN: 2223-3652; Online ISSN: 2223-3660) accepts basic and clinical science submissions related to Cardiovascular Medicine and Surgery. The mission of the journal is the rapid exchange of scientific information between clinicians and scientists worldwide. To reach this goal, the journal will focus on novel media, using a web-based, digital format in addition to traditional print-version. This includes on-line submission, review, publication, and distribution. The digital format will also allow submission of extensive supporting visual material, both images and video. The website www.thecdt.org will serve as the central hub and also allow posting of comments and on-line discussion. The web-site of the journal will be linked to a number of international web-sites (e.g. www.dxy.cn), which will significantly expand the distribution of its contents.
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