Unusually seen pattern of 99mTc-DPD soft tissue uptake in a patient with AL amyloidosis. Is it an amyloid type indicator in specific cases?

IF 0.9 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Hellenic journal of nuclear medicine Pub Date : 2022-09-01 DOI:10.1967/s002449912526
Argyrios Doumas, Iakovos Armenis, Vasileios Chatzoglou, Spyridoula Kitziri, Emmanouil Papanastasiou, Maria Koutelou
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引用次数: 0

Abstract

Technetium-99m (99mTc)-labeled pyrophosphate (PYP) and 3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) are currently the most established imaging agents for the diagnosis of cardiac amyloidosis, being able to distinguish light chain (AL) from transthyretin (TTR) type of the disease. We present a pattern of increased uptake in all soft tissues, sparing the organs that are usually most affected.

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AL淀粉样变患者99mTc-DPD软组织摄取异常。在特定情况下它是淀粉样蛋白类型的指示物吗?
锝-99m (99mTc)标记焦磷酸(PYP)和3,3-二磷酸-1,2-丙二羧酸(DPD)是目前诊断心脏淀粉样变性最成熟的显像剂,能够区分轻链(AL)和甲状腺素转甲状腺素(TTR)型疾病。我们在所有软组织中呈现出一种增加摄取的模式,保留了通常最受影响的器官。
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来源期刊
CiteScore
1.40
自引率
6.70%
发文量
34
审稿时长
>12 weeks
期刊介绍: The Hellenic Journal of Nuclear Medicine published by the Hellenic Society of Nuclear Medicine in Thessaloniki, aims to contribute to research, to education and cover the scientific and professional interests of physicians, in the field of nuclear medicine and in medicine in general. The journal may publish papers of nuclear medicine and also papers that refer to related subjects as dosimetry, computer science, targeting of gene expression, radioimmunoassay, radiation protection, biology, cell trafficking, related historical brief reviews and other related subjects. Original papers are preferred. The journal may after special agreement publish supplements covering important subjects, dully reviewed and subscripted separately.
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