Organ xenotransplantation acceptance in veterinary students: A multicentric opinion study in Spain.

IF 3.3 4区 医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL Xenotransplantation Pub Date : 2023-09-01 Epub Date: 2023-09-11 DOI:10.1111/xen.12823
Laura Martínez-Alarcón, Juan Flores-Medina, Guillermo Ramis, Jaime Gómez-Laguna, Xavier Moll, Victoria Falceto, Fidel San Román-Ascaso, Fidel San Román-Llorens, Juan José Quereda, Juan Manuel Herrero, Livia Mendonça, José Luis Martin-Barrasa, Olga María Fernández, Antonio Muñoz, Pablo Ramírez, Pedro Gutiérrez, Isabel López-Chicheri, Ana López-Navas, Antonio Ríos
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Abstract

Background: The shortage of available transplant organs has made it necessary to search for alternatives, one of which is xenotransplantation. However, the use of animal organs could face rejection from society and the personnel involved in its implementation.

Objectives: (a) to analyze the attitudes of Veterinary Degree students in six Spanish Universities towards xenotransplantation; and (b) to determine the factors that affect its acceptance.

Methods: Of the 2815 students surveyed in the degree program, 2683 valid surveys were obtained. Attitudes towards organ xenotransplantation were evaluated using a validated questionnaire of organ donation.

Results: If xenotransplantation was confirmed as a clinical reality, 93% (n = 2493) of those surveyed would accept a xenotransplanted organ, whilst 7% would not. If the results of xenotransplantation were worse than those obtained with human donors and it entailed more risk, 12% (n = 318) would be in favor. 56% (n = 1497) of the students would accept a xenotransplantation provisionally pending the arrival of a human organ. Attitudes towards xenotransplantation were affected by the academic year in which a student was studying, with more favorable attitudes among students in the last year (88% in first year vs. 95% in fifth year; p < .001). More favorable attitudes are also observed depending on the attitude they have towards organ transplantation, with those students being more in favor of donating their organs when they die (94% vs. 88%; p < .001).

Conclusion: Veterinary students would have a very favorable attitude toward xenotransplantation if these animal organs functioned as well as human organs. Therefore, these students could play an important role in the future promotion of this technique.

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兽医专业学生接受异种器官移植的情况:西班牙的一项多中心意见研究。
背景:可用移植器官的短缺使得有必要寻找替代方案,其中之一就是异种移植。然而,使用动物器官可能会遭到社会和参与实施的人员的拒绝。目的:(a)分析西班牙六所大学兽医学位学生对异种移植的态度;以及(b)确定影响其接受的因素。方法:在2815名学位课程学生中,获得2683份有效问卷。使用经验证的器官捐赠问卷评估对器官异种移植的态度。结果:如果异种移植被证实为临床现实,93%(n=2493)的受访者会接受异种移植器官,而7%的人不会。如果异种移植的结果比人类供体的结果更差,并且风险更大,12%(n=318)的人会赞成。56%(n=1497)的学生会在人体器官到达之前暂时接受异种移植。对异种移植的态度受到学生学习学年的影响,结论:如果动物器官的功能与人体器官的功能一样好,兽医专业的学生对异种移植会有非常好的态度。因此,这些学生可以在未来推广这项技术中发挥重要作用。
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来源期刊
Xenotransplantation
Xenotransplantation 医学-医学:研究与实验
CiteScore
6.80
自引率
15.40%
发文量
58
审稿时长
>12 weeks
期刊介绍: Xenotransplantation provides its readership with rapid communication of new findings in the field of organ and tissue transplantation across species barriers.The journal is not only of interest to those whose primary area is xenotransplantation, but also to veterinarians, microbiologists and geneticists. It also investigates and reports on the controversial theological, ethical, legal and psychological implications of xenotransplantation.
期刊最新文献
Xenotransplantation Literature Update December 2023–June 2024 Hendrik Jan (Henk) Schuurman, MSc, PhD (1950-2024): In Memoriam. Is Allosensitization Detrimental to Pig Organ Xenotransplantation, and Is Xenosensitization Detrimental to Subsequent Organ Allotransplantation? A Debate Organized by the International Xenotransplantation Association (IXA). Intensive Surveillance of Porcine-Rhesus Kidney Xenotransplant Using Different Ultrasound Techniques. Anti-Non-Gal Antibodies Against Porcine Protein Antigens as Barrier to Long-Term Grafting of Xenografts in Humans.
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