ASSESSMENT OF CORNEAL ENDOTHELIAL LAYER IN CONTACT LENS WEARERS WITH THE AID OF AN ENDOTHELIAL MICROSCOPE.

Q4 Medicine Ceska a Slovenska Oftalmologie Pub Date : 2022-01-01 DOI:10.31348/2022/30

P Veselý, P Beneš, J Sokolová Šidlová, P Záděrová, H Došková

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Abstract

Aims: The main aim of our study was to demonstrate the difference in endothelial cell density between a group of keratoconus contact lens users and non-contact lens users (without keratoconus).

Material and methods: In our study we had data from 96 subjects with an average age of 40.5 ±14.05 years. For the purposes of our study, we worked with each eye separately for each subject (n = 192). Keratoconus (research group) was diagnosed in 97 eyes. The mean age of the patients in the research group was 41.9 ±10.6 years. Keratoconus was not diagnosed in the remaining 95 eyes (control group). The mean age of the patients in the control group was 39.5 ±16.6 years. In the keratoconus group, the patients wore hard contact lenses (HCL) in a total of 43 eyes, hybrid contact lenses (HbCL) in 48 eyes and soft contact lenses (SCL) in 6 eyes. The average total period of contact lens use in the research group was 10.6 ±2.36 years.

Results: The average number of endothelial cells in the research group was 2607.11 ±298.45 cells per mm2. The average number of endothelial cells in the control group was 2831.94 ±523.51 cells per mm2. We tested these two variables using a T-test, which showed a statistically significant difference (p < 0.001). A statistically significant difference in the mean endothelial cell count related to patient age and use / non-use of contact lenses of two types was demonstrated only in the under-40 group in a comparison of the non-contact and keratoconus group with the keratoconus group using HCL (p = 0.02). A statistically significant difference in the length of contact lens wear was demonstrated between the keratoconus-free group with or without SCL and the keratoconus group when wearing HCL or HbCL for more than 20 years (p = 0.01 and p = 0.02). For HbCL users, this difference was demonstrated also after 15 years of wearing (p = 0.001).

Conclusion: From our results we can conclude that there is a difference in endothelial cell density between patients with and without keratoconus.

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角膜内皮显微镜对隐形眼镜佩戴者角膜内皮层的评估。

目的:我们研究的主要目的是证明一组圆锥角膜接触镜使用者和非圆锥角膜接触镜使用者(无圆锥角膜)内皮细胞密度的差异。材料与方法:我们的研究资料来自96名平均年龄为40.5±14.05岁的受试者。为了我们的研究目的，我们对每个受试者(n = 192)分别使用每只眼睛。诊断为圆锥角膜(研究组)97眼。研究组患者平均年龄41.9±10.6岁。其余95只眼(对照组)未确诊圆锥角膜。对照组患者平均年龄39.5±16.6岁。圆锥角膜组患者配戴硬质隐形眼镜(HCL) 43只眼，混合型隐形眼镜(HbCL) 48只眼，软性隐形眼镜(SCL) 6只眼。研究组佩戴隐形眼镜的平均总时间为10.6±2.36年。结果:研究组平均内皮细胞数为2607.11±298.45个/ mm2。对照组平均内皮细胞数为2831.94±523.51个/ mm2。我们使用t检验对这两个变量进行了检验，结果显示差异具有统计学意义(p <0.001)。非接触性圆锥角膜组与使用HCL的圆锥角膜组相比，仅在40岁以下的组中，与患者年龄和使用/不使用两种类型的隐形眼镜相关的平均内皮细胞计数有统计学意义(p = 0.02)。配戴HCL或HbCL超过20年时，无圆锥角膜组与不配戴SCL的圆锥角膜组的隐形眼镜佩戴时间差异有统计学意义(p = 0.01和p = 0.02)。对于HbCL使用者，这种差异在佩戴15年后也被证明(p = 0.001)。结论:从我们的结果可以得出结论，内皮细胞密度在有和没有圆锥角膜患者之间存在差异。

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来源期刊

Ceska a Slovenska Oftalmologie Medicine-Ophthalmology

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0.80

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0.00%

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