{"title":"Inhibidor del receptor de la interleucina-6 en el tratamiento de la artritis reumatoide: seguridad y dosificación del tocilizumab","authors":"Melania Martínez-Morillo, Dolors Grados, Beatriz Tejera, Alejandro Olivé Marqués","doi":"10.1016/j.semreu.2011.02.003","DOIUrl":null,"url":null,"abstract":"<div><p>Biological therapies may herald the cure for rheumatoid arthritis. Targeted biologic therapies have changed the outcome of this disease. Tocilizumab is a humanized monoclonal antibody against the interleukin-6 receptor and has been approved in many countries for the treatment of moderate to severe rheumatoid arthritis. A number of clinical trials have demonstrated the efficacy of tocilizumab in active rheumatoid arthritis. This review summarizes the data on the safety and dosage of this drug.</p></div>","PeriodicalId":101152,"journal":{"name":"Seminarios de la Fundación Espa?ola de Reumatología","volume":"12 2","pages":"Pages 57-60"},"PeriodicalIF":0.0000,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.semreu.2011.02.003","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminarios de la Fundación Espa?ola de Reumatología","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1577356611000273","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Biological therapies may herald the cure for rheumatoid arthritis. Targeted biologic therapies have changed the outcome of this disease. Tocilizumab is a humanized monoclonal antibody against the interleukin-6 receptor and has been approved in many countries for the treatment of moderate to severe rheumatoid arthritis. A number of clinical trials have demonstrated the efficacy of tocilizumab in active rheumatoid arthritis. This review summarizes the data on the safety and dosage of this drug.
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