J. Halámek, P. Jurák, P. Veselý, V. Vondra, P. Leinveber
{"title":"The analysis of linear/nonlinear coupling between heart rate and QT intervals","authors":"J. Halámek, P. Jurák, P. Veselý, V. Vondra, P. Leinveber","doi":"10.1109/ESGCO.2014.6847517","DOIUrl":null,"url":null,"abstract":"Two groups of subjects (21 healthy, 21 hypertensive patients) were tested during two measurement protocols (exercise, tilt). Two models of QT-RR coupling were tested - linear (LM) and nonlinear (NLM). QTc reproducibility was used as evidence of model validity. Results: LM was significantly better (lower QTc irreproducibility) than NLM (P<;0.01) during the tilt-table test. The differences were not significant during the exercise test; NLM was slightly better in hypertensive patients, LM in healthy subjects. Maximal irreproducibility of QTc over subjects was found in both tests with NLM. Conclusion: Evidence of QT-RR nonlinearity cannot be based on minimal error between QT and model QT. QTc reproducibility must also be tested and the excitation specificity of QT-RR coupling must be considered.","PeriodicalId":385389,"journal":{"name":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","volume":"35 2","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2014-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ESGCO.2014.6847517","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Two groups of subjects (21 healthy, 21 hypertensive patients) were tested during two measurement protocols (exercise, tilt). Two models of QT-RR coupling were tested - linear (LM) and nonlinear (NLM). QTc reproducibility was used as evidence of model validity. Results: LM was significantly better (lower QTc irreproducibility) than NLM (P<;0.01) during the tilt-table test. The differences were not significant during the exercise test; NLM was slightly better in hypertensive patients, LM in healthy subjects. Maximal irreproducibility of QTc over subjects was found in both tests with NLM. Conclusion: Evidence of QT-RR nonlinearity cannot be based on minimal error between QT and model QT. QTc reproducibility must also be tested and the excitation specificity of QT-RR coupling must be considered.
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