Cancro Renal associado ao Trabalho

Mónica Santos, A. Almeida, Catarina Lopes
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Abstract

Introduction/framework/objectives There are several cancers that can be associated with some characteristics of the Work. Regarding the oncological pathology of the Kidney, there are not many publications. The aim of this review was to summarize what has been reported on the subject to date, in order to enhance the performance of Occupational Health and Safety Teams working in possibly targeted sectors. Methodology This is a Bibliographic Review, initiated through a search carried out in January 2022 in the databases “CINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: comprehensive, MedicLatina and RCAAP”. Content Kidney Cancer, at the level of non-occupational etiology, may be associated with tobacco, obesity and high blood pressure (metabolic syndrome), as well as Cystic Kidney Disease, male gender, older age, black ethnicity and family history. It is believed that tobacco can explain 20 to 30% of it in men and 10 to 20% in women; being the dose-dependent relationship. The association with arterial hypertension also seems to be dose-dependent and more intense above 160 and 100 mmHg for systolic and diastolic, respectively. There are several working conditions capable of enhancing it; even so, studies sometimes do not consider the possible influence of biasing variables, such as smoking, including passive. Discussion and Conclusions Although without absolute consensus, this cancer seems to be enhanced by exposure to Radon/Uranium, Asbestos, Pesticides, derivatives of Fuels and various Chemical Agents (such as tri and tetrachlorethylene, dinitrotoluene and lead). Thus, the most targeted professional sectors could be mining; civil and naval construction, demolition sector; agriculture; production, packaging and distribution of relevant chemical agents; refineries and filling stations; as well as dry cleaning, printing, car and aircraft mechanics, maintenance, metallurgy, drivers and road pavers. It would be pertinent for some Occupational Health and Safety teams to initiate research projects in this context, for subsequent dissemination of conclusions, in order to advance knowledge and provide a healthier and safer work environment. KEYWORDS: kidney cancer, occupational health, occupational medicine and safety at work.
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与工作有关的肾癌
引言/框架/目标有几种癌症可以与工作的某些特征相关联。关于肾脏的肿瘤学病理,目前文献不多。本次审查的目的是总结迄今为止关于这一主题的报告,以提高职业健康和安全小组在可能的目标部门工作的绩效。这是一篇文献综述,通过检索于2022年1月启动的数据库“CINALH plus全文、Medline全文、效果评价摘要数据库、Cochrane对照试验中央登记、Cochrane系统评价数据库、Cochrane方法学登记、护理和联合健康Collection: comprehensive、MedicLatina和RCAAP”。在非职业病因方面,肾癌可能与烟草、肥胖和高血压(代谢综合征)以及囊性肾病、男性、年龄较大、黑人种族和家族史有关。据信,烟草可以解释20%至30%的男性和10%至20%的女性;是剂量依赖关系。与动脉高血压的关联似乎也是剂量依赖性的,收缩压和舒张压分别高于160和100 mmHg时更为强烈。有几种工作条件能够提高它;即便如此,研究有时也没有考虑到包括被动吸烟在内的偏倚变量可能产生的影响。讨论和结论虽然没有绝对共识,但这种癌症似乎因暴露于氡/铀、石棉、农药、燃料衍生物和各种化学制剂(如三氯乙烯和四氯乙烯、二硝基甲苯和铅)而加剧。因此,最具针对性的专业部门可能是采矿业;民用和海军建筑、拆除部门;农业;相关化学制剂的生产、包装和经销;炼油厂和加油站;以及干洗,印刷,汽车和飞机机械,维修,冶金,司机和道路摊铺者。一些职业健康和安全小组应在这方面开展研究项目,随后传播结论,以便增进知识,提供更健康和更安全的工作环境。关键词:肾癌、职业健康、职业医学与工作安全。
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