{"title":"Remote switching of cellular activity using light through quantum dots","authors":"K. Lugo, X. Miao, F. Rieke, Lih Y. Lin","doi":"10.1109/OMEMS.2010.5672180","DOIUrl":null,"url":null,"abstract":"We report integration of CdTe quantum dot (QD) film with LnCap (prostate cancer) cell and CdSe QD probes with cortical neurons for control of cellular activity. We demonstrate the remote switching of cellular activity by exciting QDs with light. Changes in membrane potential and ionic currents are recorded using the patch-clamp method. Upon excitation, the cell shows activation of ion channels and hyperpolarization of the cell membrane.","PeriodicalId":421895,"journal":{"name":"2010 International Conference on Optical MEMS and Nanophotonics","volume":"415 2","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2010-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2010 International Conference on Optical MEMS and Nanophotonics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/OMEMS.2010.5672180","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We report integration of CdTe quantum dot (QD) film with LnCap (prostate cancer) cell and CdSe QD probes with cortical neurons for control of cellular activity. We demonstrate the remote switching of cellular activity by exciting QDs with light. Changes in membrane potential and ionic currents are recorded using the patch-clamp method. Upon excitation, the cell shows activation of ion channels and hyperpolarization of the cell membrane.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
