EVALUATION OF ANTIMUTAGENIC, ANTIMICROBIAL AND PLANT GROWTH PROMOTION ACTIVITIES OF STREPTOMYCES SPP.

Abstract

The present study is concentrated on the evaluation of antimutagenic, antimicrobial and plant growth promotion potential of Streptomyces spp. viz. Streptomyces violascens strain OS-6 and Streptomyces sp. strain TES-25. The chloroform and ethyl acetate extracts of both the strains were prepared. In the UHPLC analysis, the extracts revealed the presence of various polyphenolic compounds. The extracts exhibited potent antimutagenic potential in Ames assay against two tester strains of Salmonella typhimurium TA98 and TA100 in case of pre incubation mode with metabolic activation. The extracts showed considerable antibacterial and antifungal activities against the tested bacteria and fungal phytopathogens respectively. The treatment of wheat seeds with both strains resulted in the enhancement of growth parameters of wheat such as root length, shoot length, number of plants, fresh weight per plant, dry weight per plant, fresh weight per tiller, dry weight per tiller, number of tillers per plant and number of seeds per plant. The present work recommends the use of strains in the pharmaceutical drug formulations for the treatment of different diseases and as bio-fertilizer for enhancing the growth and yield of plants.