Stem Cell Biology on Autoimmune Disease-Crohn’s Disease, Complex Pathogenesis Cure through Regenerative Disease

Prithiv K R Kumar
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Abstract

The attack on immune system in the gut which leads to bowel obstruction, severe diarrhoea, rectal bleeding are major symptoms in individual’s intestinal tissue. This disease is Crohn’s disease. The inflammation in the intestine is caused due to mucosal immune reactivity to antigen found in the lumen. The cost of cure is significantly higher in terms of health care. Now there is a chance for exploration of stem cell cure for Crohn’s disease. Although surgical restructure is required, the disease seems to appear even after surgery. It rejects restructuring unit. Hence surgery is often a failure. After careful experiments on CD patients, Mesenchymal Stem Cells and Hemopoietic Stem Cells are the best available options to cure CD. This case study shows how stem cells works and its results. The results have restructured the way stem cells have been to put to best use in patients that suffer the most with CD. At certain point, the results have high effects in its clinical emission with no medication required. CD patients had adverse effects while in medication and no serious effects with no medication. The definition of stem cells has been smeared all over this Crohn Disease patients and the results have been amazing.
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自身免疫性疾病-克罗恩病的干细胞生物学,通过再生疾病治疗复杂的发病机制
肠道免疫系统受到攻击,导致肠梗阻、严重腹泻、直肠出血是个体肠道组织的主要症状。这种病是克罗恩病。肠道炎症是由于粘膜对管腔内抗原的免疫反应引起的。就医疗保健而言,治疗费用要高得多。现在有机会探索干细胞治疗克罗恩病。虽然需要手术重建,但这种疾病似乎在手术后也会出现。它拒绝重组单位。因此手术常常是失败的。经过对乳糜泻患者的仔细实验,间充质干细胞和造血干细胞是治疗乳糜泻的最佳选择。本案例研究展示了干细胞的工作原理及其结果。研究结果重塑了干细胞的使用方式,使其能够在最严重的乳糜泻患者中发挥最大的作用。在某种程度上,该结果在临床释放方面具有很高的效果,无需药物治疗。乳糜泻患者在服药期间有不良反应,未服药时无严重反应。干细胞的定义被涂抹在克罗恩病患者身上,结果是惊人的。
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