Utilisation of an embedded resonant structure to differentiate Lipomyces yeast cultures based upon lipid content and concentration

Abstract

This article proposes a method for differentiation of biological samples based upon the dielectric characteristics of the sample. Lipid accumulation within cells is significant as it serves as a marker pertaining to the metabolism and oncologic state of the cell and organism. This is accomplished through dielectric characterisation of the sample utilising circuit board based resonant structures. This paper presents a preliminary experiment using lipid accumulating yeast cultures to model lipid droplets in mammalian cells. The experiment indicated that lipid positive and negative cultures can be differentiated based upon the dielectric characteristics of the sample.