Risk factors and management strategies for atrial fibrillation

Duaa Durrani, R. Fatima, M. Shaikh
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Abstract

Atrial fibrillation (AF) is a cardiac arrhythmia characterised by the irregular and frequently fast depolarization of the atrial myocardium resulting from a disturbance of the usual electrical conduction routes within the atria, which causes disorganised and ineffective atrial contractions. The management of AF involves a multidisciplinary approach that includes identifying and treating underlying risk factors, managing symptoms, and preventing complications. The risk factors for AF include age, hypertension, obesity, diabetes mellitus, valvular heart disease, coronary artery disease, congestive heart failure, alcohol consumption, sleep apnea, and family history. The management strategies for AF include rate control, rhythm control, anticoagulation, left atrial appendage closure, lifestyle modifications, surgical ablation, catheter ablation, cardioversion, and education and support. The choice of management strategy should be tailored to the individual patient’s risk profile, comorbidities, and other factors. Further research is needed to improve our understanding of the pathophysiology of AF and to develop more effective management strategies for this condition.
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房颤的危险因素及治疗策略
心房颤动(AF)是一种心律失常,其特征是心房心肌不规则且经常快速去极化,这是由于心房内通常的电传导路线受到干扰,导致心房收缩紊乱和无效。房颤的治疗涉及多学科的方法,包括识别和治疗潜在的危险因素、控制症状和预防并发症。房颤的危险因素包括年龄、高血压、肥胖、糖尿病、瓣膜性心脏病、冠状动脉疾病、充血性心力衰竭、饮酒、睡眠呼吸暂停和家族史。房颤的治疗策略包括心率控制、心律控制、抗凝、左心耳关闭、生活方式改变、手术消融、导管消融、心律转复、教育和支持。管理策略的选择应根据个体患者的风险概况、合并症和其他因素进行调整。需要进一步的研究来提高我们对房颤病理生理的理解,并制定更有效的治疗策略。
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