Frequency and severity of symptoms in patients with Fibromyalgia and Migraine

D. Castrillon Bustamante, A. Secco, O. P. Campos, Erick Rodríguez Bossio, N. Callahuara
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Abstract

Objectives: to estimate the frequency of migraine in patients with fibromyalgia (FM). Describe and compare clinical characteristics, sociodemographic and severity of FM symptoms, according to presence or absence of migraine. Materials and methods: analytical, observational, cross-sectional study. It included patients over 18 years of age, of both sexes with a diagnosis of FM according to ACR 2010 criteria from a public rheumatology center in Argentina between January 2019 and March 2020. Patients with other concomitant rheumatological diseases were excluded. We used IHS (International Headache Society) criteria for the diagnosis of migraine, FIQ (fibromyalgia Impact Questionnaire) were used to assess severity of symptoms. Results: 59 patients were included, 99% were women. 40.68% of the patients had migraine. In patients with migraine, the median FIQ score was 70.35 (IQR: 63.16-78.76) vs 53.91 (IQR: 37.93-66.05) in the group without migraine, this difference being statistically significant (p<0.01). The multivariate analysis showed a higher FIQ and anxiety score, significantly and independently associated with migraine (OR 1.048, 95% CI 1.005-1.093); OR 1,189, 95% CI 1,033-1,368, respectively). Conclusions: migraine is frequent in patients with FM, and the severity of symptoms and anxiety would be more pronounced in this group of patients.
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纤维肌痛和偏头痛患者症状的频率和严重程度
目的:估计纤维肌痛(FM)患者偏头痛的发生频率。根据偏头痛的存在与否,描述和比较FM症状的临床特征、社会人口学和严重程度。材料和方法:分析性、观察性、横断面研究。该研究包括2019年1月至2020年3月期间阿根廷一家公共风湿病中心根据ACR 2010标准诊断为FM的18岁以上男女患者。排除伴有其他风湿病的患者。我们使用IHS(国际头痛学会)标准诊断偏头痛,FIQ(纤维肌痛影响问卷)评估症状的严重程度。结果:纳入59例患者,其中99%为女性。40.68%的患者有偏头痛。偏头痛患者FIQ评分中位数为70.35 (IQR: 63.16-78.76) vs非偏头痛组53.91 (IQR: 37.93-66.05),差异有统计学意义(p<0.01)。多变量分析显示,较高的FIQ和焦虑评分与偏头痛显著且独立相关(OR 1.048, 95% CI 1.005-1.093);OR 1189, 95% CI分别为1033 - 1368)。结论:偏头痛多发于FM患者,且此组患者的症状和焦虑程度更为明显。
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