Covid-19 With Cerebrovascular Manifestations: Review of Literature and Case Series

Mukesh Patel, Himanshu Raval
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Abstract

Background: In year 2020, we are fighting with global threat of corona virus pandemic. It is more hazardous with its heterogeneous presentation involving all systems in body. Objective: As corona virus having properties to produce cerebrovascular diseases via causing hypercoaguable state and possible endothelial damage, it is necessary to look this facet of its virulence. Here, we are presenting review of literature and case series of three patients having covid stroke, two of which having ischemic stroke and one of them is having hemorrhagic stroke. Methods and Material: This study has been carried out at SVP hospital Ahmedabad which is designated covid care hospital in western India from March to august. With no proper etiopathogenesis established between covid-19 and stroke, this data is useful as obtained from dedicated covid hospital in western India with drainage area of approximately 6,00,00,000 population. Result: Mortality is higher in patients with cerebrovascular manifestation with hypercoagulability and thrombotic complications. Conclusion: Neurological examination must be given proper importance in apparently well covid-19 positive patients to reveal minute neurological clues. A centralized database needed to be established at national level. Once covid-19 can be established as direct causative agent, a term “covid stroke” must be given proper importance and guideline can be formed for treatment.
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伴有脑血管症状的Covid-19:文献综述和病例系列
背景:2020年,我们正在与冠状病毒大流行的全球威胁作斗争。更危险的是,它的异质表现涉及到身体的所有系统。目的:由于冠状病毒具有通过引起高凝状态和可能的内皮损伤而导致脑血管疾病的特性,因此有必要对其毒力进行研究。在这里,我们将对3例新冠肺炎卒中患者的文献和病例系列进行回顾,其中2例为缺血性卒中,1例为出血性卒中。方法和材料:本研究于3月至8月在印度西部指定的covid护理医院艾哈迈达巴德SVP医院进行。由于没有确定covid-19与中风之间的病因,因此从印度西部的专门医院获得的数据是有用的,该医院的排水面积约为60万人口。结果:伴有高凝和血栓形成并发症的脑血管患者死亡率较高。结论:对表面健康的covid-19阳性患者应重视神经学检查,以发现微小的神经学线索。需要在国家一级建立一个中央数据库。一旦确定covid-19为直接病因,就必须对“covid -中风”一词给予适当重视,形成治疗指南。
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