{"title":"Improved method for preparation of S9-activated heterocyclic amines","authors":"S. Arimoto-Kobayashi, H. Hayatsu","doi":"10.3123/JEMS.25.77","DOIUrl":null,"url":null,"abstract":"We investigated improved methods for the preparation of metabolically activated forms of heterocyclic amines referred to as ‘activated heterocyclic amines’. We also described the influence of pH on the metabolic activation of Trp-P-2, and on the stability and mutagenicity of the activated form of Trp-P-2.","PeriodicalId":394432,"journal":{"name":"Environmental Mutagen Research","volume":"45 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2003-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental Mutagen Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3123/JEMS.25.77","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
We investigated improved methods for the preparation of metabolically activated forms of heterocyclic amines referred to as ‘activated heterocyclic amines’. We also described the influence of pH on the metabolic activation of Trp-P-2, and on the stability and mutagenicity of the activated form of Trp-P-2.
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