{"title":"Ultrasensitive electronic detection of DNA using Si nanograting FETs coated with PNA probes","authors":"S. Regonda, L. Spurgin, Walter Hu","doi":"10.1109/NANO.2013.6720911","DOIUrl":null,"url":null,"abstract":"We report the label-free rapid detection of single stranded DNA segments using lithographic Si nanograting (NG) FET devices coated with single stranded PNA probes. The NGFETs shows improved signal to noise ratio and similar sensitivity in comparison with the single nanowire FETs fabricated on the same chip. The limit of detection of our finFETs reaches sub-femtoMolar. The same devices do not respond significantly to high concentrations of non-complementary DNA segments.","PeriodicalId":189707,"journal":{"name":"2013 13th IEEE International Conference on Nanotechnology (IEEE-NANO 2013)","volume":"56 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2013-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2013 13th IEEE International Conference on Nanotechnology (IEEE-NANO 2013)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/NANO.2013.6720911","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
We report the label-free rapid detection of single stranded DNA segments using lithographic Si nanograting (NG) FET devices coated with single stranded PNA probes. The NGFETs shows improved signal to noise ratio and similar sensitivity in comparison with the single nanowire FETs fabricated on the same chip. The limit of detection of our finFETs reaches sub-femtoMolar. The same devices do not respond significantly to high concentrations of non-complementary DNA segments.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
