Meta-analysis and Network Analysis of Five Ovarian Cancer Gene Expression Dataset

Hua Dong, Shengjun Hong, Xiaomin Xu, Yanghua Xiao, Li Jin, M. Xiong
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引用次数: 4

Abstract

Ovarian cancer is the fifth leading cause of death from cancer in women and the leading cause of death from gynecological cancer. Here we present a meta-analysis of five gene expression data sets of 432 ovarian cancer and 42 adjacent normal samples in total. We indentified 3 genes: NDN, RNASE4, IGFBP4 were significantly differentially expressed in both five data sets. After combined the dataset by meta-analysis, 3722 genes were significant (p-value
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五种卵巢癌基因表达数据集的meta分析和网络分析
卵巢癌是妇女癌症死亡的第五大原因,也是妇科癌症死亡的主要原因。在此,我们对432例卵巢癌和42例相邻正常样本的5个基因表达数据集进行了荟萃分析。我们发现3个基因:NDN, RNASE4, IGFBP4在这5个数据集中有显著差异表达。对数据集进行meta分析后,有3722个基因显著(p值)
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