Proteins in bronchial secretion of children with chronic pulmonary diseases. I. Relation to clinical diagnosis.

J Gaweł, J Rudnik, J Pryjma, J Zebrak, J Hałuszka, I Rudnik, H Majewska-Zalewska
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引用次数: 0

Abstract

Bronchial secretions from 207 children suffering from various pulmonary diseases and from 15 healthy controls were tested concentration of IgA, IgG, lactoferrin and lysozyme. The results obtained suggest that in many cases of chronic lung diseases in children the levels of lactoferrin and immunoglobulins, especially secretory IgA, are very low. In severe infections (cystic fibrosis, bronchiectases) significant increase of IgG concentration was observed.

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慢性肺部疾病患儿支气管分泌物中的蛋白质。1 .与临床诊断的关系。
对207例肺部疾病患儿和15例健康对照者的支气管分泌物进行了IgA、IgG、乳铁蛋白和溶菌酶浓度检测。所获得的结果表明,在许多慢性肺部疾病的儿童中,乳铁蛋白和免疫球蛋白的水平,特别是分泌性IgA的水平非常低。严重感染(囊性纤维化、支气管扩张)时IgG浓度显著升高。
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