O. Gerzen, I. Simanova, S. Nabiev, L. Nikitina, I. Selezneva
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引用次数: 1
Abstract
Lead intoxication was modelled by intraperitoneal injection of lead acetate to rats 3 times a week during 5 weeks. The velocity of thin filaments movement at different calcium concentrations over myosin extracted from the right ventricle of the rats’ hearts of control group and group with lead intoxication was estimated using an in vitro motility assay. Lead intoxication reduced the maximum velocity of movement by 30% because of the shift of myosin isoforms towards slow ones and did not influence on calcium regulation.
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