Development of analytical method for pesticide residue determination using LC-MS/MS

M. Prodhan, A. Begum, M. Afroze, M. Ahmed, N. K. Dutta, D. Sarker
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引用次数: 3

Abstract

This study was initiated to develop an accurate analytical method for the determination of neonicotinoid and organophosphorus insecticide using Liquid Chromatography tandem Mass Spectrometry (LC-MS/MS). Several experiments were conducted to select the parent ion and precusor ion and based on this outcome, the analytical method for the determination of thiamethoxam and dimethoate using LC-MS/MS was developed. The heated electrospray ionization (HESI) mode was used to develop the method.  The linearity of the developed analytical method was very good and it was 0.998 for both of the selected pesticides. The optimization of MS/MS parameters has been done properly for both of the selected pesticides through direct infusion of 100 ug/L standard solutions. Asian Australas. J. Food Saf. Secur. 2022, 6 (2), 65-72
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LC-MS/MS测定农药残留分析方法的建立
本研究旨在建立液相色谱串联质谱法(LC-MS/MS)测定新烟碱类和有机磷类杀虫剂的准确分析方法。通过多次实验选择母体离子和前驱离子,在此基础上建立了hplc -MS/MS法测定噻虫嗪和乐果的分析方法。采用加热电喷雾电离(HESI)模式来开发该方法。所建立的分析方法线性关系良好,两种农药的线性关系均为0.998。通过直接滴注100 ug/L标准溶液,对所选农药进行了MS/MS参数优化。亚洲Australas。J.食品安全。安全,2022,6 (2),65-72
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