Functional state of adrenergic innervation of the stomach in rats with different stability of cardiovascular functions in experimental stress.

Abstract

Stress is induced in male Wistar and August rats by immobilising them for 30 hours. Nerve endings were studied using the method of fluorescent microscopy of Falck and Owman, modified by E. M. Krokhina. These studies showed that the dystrophic process related to stress acts on the activation system of the adrenergic innervation. This activation of transmitter synthesis in all the neurones is related to the large number of adrenergic transmitter substances found in the stomach wall. There are differences between animal species: August rats are more sensitive. This no doubt reflects a general instability in the vegetative functions of this species. The authors conclude that depending on the animal species there are factors in the stomach which may either afford resistance or predispose the organism to disorders of the cardiovascular system.