Two-wavelength excitation spectroscopy for non-invasive detection of the iron deficiency indicator zinc protoporphyrin IX

H. Stepp, Christian Homann, G. Hennig, M. Vogeser
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Abstract

Increased formation of fluorescent zinc protoporphyrin IX (ZnPP) inside erythrocytes indicates functional iron deficiency. Two-wavelength excitation spectroscopy detects ZnPP even through intact skin. Its suitability was successfully tested in women, surgical patients, infants and blood donors.
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无创检测缺铁指示剂原卟啉锌的双波长激发光谱
红细胞内荧光锌原卟啉IX (ZnPP)的形成增加表明功能性铁缺乏。双波长激发光谱检测ZnPP甚至通过完整的皮肤。在妇女、外科病人、婴儿和献血者中成功地测试了其适用性。
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