Kaplan-Meier And Cox Regression Analyses of Exclusive Breastfeeding Discontinuation In Mansoura, Egypt

A. El-Gilany, D. Abdel-Hady, Doaa H. Abdelhady
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引用次数: 1

Abstract

Background: Exclusive breastfeeding (EBF) is the single most cost-effective intervention to reduce infant mortality in developing countries. However, most studies concluded that a large proportion of infants are not exclusively breastfed. Objectives: to estimate duration of EBF using Kaplan-Meier analysis and to find out the independent factors associated with early cessation of EBF. Method: A cross-sectional descriptive study was carried out on 884 motherinfant pairs during vaccination at age of six months in Mansoura District, Egypt. Data collected are: sociodemographic characteristics of mothers, infants their families, antenatal, natal and postnatal data. Kaplan Meier estimator were used to produce valid estimates of EBF duration and the Cox’s proportional hazards model was fitted to identify risks of early EBF discontinuation. Results: At six months 14.8% of infants are still exclusively breastfed. The median period of EBF was 4.0 months. The independent risk factors of EBF discontinuation are maternal work (Adjusted Hazard Ratio (AHR)=1.6, Confidence Interval (CI)=1.3-1.9), preterm births AHR=1.4, CI=1.1-1.1), urban residence (AHR=1.3, CI=1.1-1.5) and being female infant (AHR=1.2, CI=1.1-1.4). Conclusion: The median duration of EBF is below the recommended; and early discontinuation was associated with many factors that should be considered in designing breast feeding promotion programs.
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Kaplan-Meier和Cox回归分析在曼苏拉,埃及纯母乳喂养停止
背景:纯母乳喂养(EBF)是发展中国家降低婴儿死亡率的唯一最具成本效益的干预措施。然而,大多数研究得出的结论是,很大一部分婴儿没有得到纯母乳喂养。目的:利用Kaplan-Meier分析估计EBF持续时间,并找出与EBF早期停止相关的独立因素。方法:对埃及曼苏拉地区884对6个月大接种疫苗的母婴进行横断面描述性研究。收集的数据包括:母亲、婴儿及其家庭的社会人口特征、产前、分娩和产后数据。使用Kaplan Meier估计器对EBF持续时间进行有效估计,并拟合Cox比例风险模型来识别早期EBF中断的风险。结果:在6个月时,14.8%的婴儿仍然是纯母乳喂养。EBF的中位时间为4.0个月。中断EBF的独立危险因素为产妇工作(调整风险比(AHR)=1.6,置信区间(CI)=1.3 ~ 1.9)、早产AHR=1.4, CI=1.1 ~ 1.1)、城市居住(AHR=1.3, CI=1.1 ~ 1.5)和女婴(AHR=1.2, CI=1.1 ~ 1.4)。结论:EBF的中位持续时间低于推荐值;早期停药与许多因素有关在设计母乳喂养促进方案时应考虑这些因素。
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