{"title":"Antenatal Magnesium Sulphate Infusion for Neuroprotection of Preterm Babies","authors":"Bashu Dev Parajuli","doi":"10.59881/jpeson11","DOIUrl":null,"url":null,"abstract":"The incidence of cerebral palsy (CP) before the age of 2 years is highest among the preterm babies. Neuroprotection in preterm babies is challenging. There are various proposed mechanisms but antenatal magnesium sulphate (MgSo4 ) infusion for 4 to 24 hours predelivery has shown to reduce the incidence of CP at the cost of bearable minor maternal and fetal side-effects. The practice of antepartum infusion of MgSo4 is adopted by various guidelines and societies, including World Health Organization (WHO).","PeriodicalId":158871,"journal":{"name":"Journal of Perinatal Society of Nepal","volume":"81 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Perinatal Society of Nepal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.59881/jpeson11","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The incidence of cerebral palsy (CP) before the age of 2 years is highest among the preterm babies. Neuroprotection in preterm babies is challenging. There are various proposed mechanisms but antenatal magnesium sulphate (MgSo4 ) infusion for 4 to 24 hours predelivery has shown to reduce the incidence of CP at the cost of bearable minor maternal and fetal side-effects. The practice of antepartum infusion of MgSo4 is adopted by various guidelines and societies, including World Health Organization (WHO).
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