Evaluation of Anticonvulsant Activity of Allapinine and N-Deacetylappaconitine in Experimental Animals.

Z. I. Sanoev, T. T. Khamroev, Ibrokhim Tuychievich Abdinazarov, S. Z. Rashidov, S. D. Rakhimboev
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引用次数: 1

Abstract

The present article presents a research paper on the evaluation of anticonvulsant activity of allapinine and N-debacetylappaconitine with high antiarrhythmic activity caused at different doses and with different analyzers. The results of the conducted studies showed that allapinine and N-debacetylappaconitine are not inferior and even slightly superior to carbamazepine in anticonvulsant activity. In this regard, based on the conducted studies, it can be concluded that allapinin affects not only cardiomyocytes, but also ion exchange in nerve cells.
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Allapinine和n - deacetylapaponitine在实验动物中的抗惊厥活性评价。
本文研究了高抗心律失常活性的allapinine和n -去乙酰apaponitine在不同剂量和不同分析物作用下的抗惊厥活性的评价。所进行的研究结果表明,allapinine和N-debacetylappaconitine的抗惊厥活性不低于卡马西平,甚至略优于卡马西平。对此,根据已有的研究可以得出结论,allapinin不仅影响心肌细胞,还影响神经细胞中的离子交换。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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