Dengue: An Overview of Pathogenesis and Analysis of Disease

Nida Naeem, Muhammad Obaid Tahir, Taha Mobeen, Lahrasb Khan, Amna Mahmood
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Abstract

Dengue as a viral infection was or is a serious issue. With the time this viral infection changes within it’s environment. Researches are conducted to completely know the genome of dengue as well as it’s long lasting treatment. Both flaviviruses and mammalian cells produce NS1 and induce strong humoral responses in circulation. NS1 levels correlate with viral titer and can be used as a viremia marker. The disappearance of NS1 at high concentrations between low nanograms per milliliter and micrograms per milliliter was determined using numerical ELISA detection. NS1 levels as high as 600 nanograms per milliliter during secondary infection have been found to indicate high levels of severe disease within his first 72 hours of illness
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登革热:发病机制概述和疾病分析
登革热作为一种病毒感染过去或现在都是一个严重的问题。随着时间的推移,这种病毒感染在它的环境中发生了变化。进行研究是为了完全了解登革热的基因组以及它的长期治疗。黄病毒和哺乳动物细胞都产生NS1,并在循环中诱导强烈的体液反应。NS1水平与病毒滴度相关,可作为病毒血症标志物。采用数值ELISA法测定NS1在低纳克/毫升至微克/毫升高浓度下的消失量。在继发性感染期间,NS1浓度高达每毫升600纳克这表明他在发病的前72小时内患有严重的疾病
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