A microstructured fiber for streptavidin detection

F. Khozeymeh, F. Melli, Sabrina Capodaglio, R. Corradini, F. Benabid, L. Vincetti, A. Cucinotta
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Abstract

The properties of the microstructured optical fibers (MOFs) make them a growing photonics sensing platform with a wide range of applications in medicine, biological, and chemical detection. Particularly in the detection of bio/chemical analytes using the MOFs, the main advantage is the integration of the optical transducer and fluidic part in the unique MOF platform. In this work, we report a Kagome-based lattice MOF for the detection of streptavidin molecules. Interaction between the light coupled into the fiber in form of the LP-like modes and analytes attached to the fiber’s internal surface will result in the analyte detection. This study shows that the Kagome-based MOFs can be used for protein molecule detection.
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一种用于链霉亲和素检测的微结构纤维
微结构光纤(MOFs)的特性使其在医学、生物和化学检测领域具有广泛的应用前景。特别是在使用MOF检测生物/化学分析物时,其主要优势是将光学传感器和流体部分集成在独特的MOF平台中。在这项工作中,我们报道了一种基于kagome的晶格MOF,用于检测链霉亲和素分子。以类lp模式耦合到光纤中的光与附着在光纤内表面的分析物之间的相互作用将导致对分析物的检测。本研究表明,基于kagome的mof可用于蛋白质分子检测。
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