Dural sinus thrombosis: pre- and postnatal MRI observation

A. Korostyshevskaya, A. M. Gornostaeva, A. Makogon, A. Khalikov
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Abstract

Highlights. The clinical case report describes the important role of MRI in the perinatal diagnosis of dural sinus thrombosis, timely verification of the diagnosis, differential diagnosis with other vascular and tumor formations of the brain.Abstract. Dural sinus thrombosis (DST) is a rare congenital anomaly. Ultrasound findings usually mimic intracranial tumors. As a result, the condition is often misdiagnosed and its frequency in general population is underestimated. According to literature data, the progression of DST is a favorable prognosis in case of absence of other concomitant pathologies of the fetal brain. We present a case of DST that was detected with ultrasound, and verified by numerous pre and postnatal MRI starting from 22 weeks of gestation till 4 years of life. A case with a favorable neurological outcome, postnatal ventriculosubgaleal shunting, and ventriculoperitoneal shunting was followed with MRI and CT before and after interventions. The aspects of differential diagnosis, factors determining prognosis are presented. The presented case demonstrates a significant role of fetal MRI in DST diagnosis, depiction of the internal structure of the expanded sinus, and exclusion of concomitant pathology of the brain. These MRI data are integral in determining the appropriate perinatal management, and can be used as predictors of the favorable neurological outcome despite of the severity and size of prenatally diagnosed DSТ.
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硬脑膜窦血栓形成:产前和产后MRI观察
高光。本临床病例报告阐述了MRI在围生期诊断硬脑膜窦血栓形成、及时证实诊断、与脑其他血管及肿瘤形成鉴别诊断中的重要作用。硬脑膜窦血栓形成是一种罕见的先天性异常。超声表现通常与颅内肿瘤相似。因此,这种情况经常被误诊,其在一般人群中的频率被低估。根据文献资料,在没有其他胎儿脑病变的情况下,DST的进展是一个良好的预后。我们提出了一例DST,超声检测,并通过大量产前和产后MRI证实,从妊娠22周开始,直到4岁。我们在干预前后分别用MRI和CT对1例神经学预后良好的新生儿脑室-腓骨下分流和脑室-腹膜分流进行了随访。提出了鉴别诊断、决定预后的因素等方面。本病例证明了胎儿MRI在DST诊断、扩张窦内部结构的描述和排除脑伴随病理方面的重要作用。这些MRI数据在确定适当的围产期管理中是不可或缺的,尽管产前诊断的严重程度和大小DSТ,但可以用作有利的神经预后的预测因子。
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