Stigmasterol in Health and Disease: A Review

Biswas Sj
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Abstract

Stigmasterol (STG) is steroid alcohol that belongs to the group of phytosterols of the plant. It has different biological properties and considered a popular medicinal compound throughout the world. STG has established and emerging health benefits including anti-inflammatory activity, immunomodulatory effect, antiviral, antimicrobial, antifungal activities, possess positive modulatory effect on CNS, anticancer effect, hepatoprotective, antioxidant, antidiabetic, acaricidal activities. STG also has some negative and toxic effects such as accumulation of STG causes cardiac injury thereby causing mortality. This review overall describes the structure, source, function, mode of action and various pharmacological properties so that it can serve as a reference tool for other investigators working in the area.
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豆甾醇在健康和疾病中的研究进展
豆甾醇(STG)是一种甾体醇,属于植物甾醇类。它具有不同的生物学特性,被认为是世界各地流行的药用化合物。具有抗炎、免疫调节、抗病毒、抗菌、抗真菌、中枢神经系统正向调节、抗癌、保肝、抗氧化、降糖、杀螨等已证实的健康益处。STG也有一些负面和毒性作用,如STG的积累会引起心脏损伤,从而导致死亡。本文对其结构、来源、功能、作用方式和各种药理特性进行了全面的介绍,以期为该领域的其他研究者提供参考。
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