Changes of Corneal Thickness and Intraocular Pressure in Type II Diabetic Patients

Yasmena Abdulhadi
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Abstract

Aims. The purpose of the present paper is to present the results of central corneal thickness & intraocular pressure measurements in diabetic patients with or without retinopathy, and compare the results with non-diabetic control patients. Methods. Total number was 152 patients were 152 eyes The study group was divided into 3 groups as following: 50 non diabetic (control). 50 diabetic type II with no diabetic retinopathy. 52 diabetic type II patient with diabetic retinopathy. Correlation analysis was performed to assess the association between glycosylated hemoglobin levels& Intraocular pressures and retinal changes among subgroups. Results. Demographic characteristics of study and control groups were similar (P>0.05). Mean CCT 553.62 with Std deviation (14.47) in control cases and 622.27 with Std deviation (507.09) in diabetic cases which is more than control however the distinction failed to reach applied math significance were (p value= > 0.05). additionally, CCT and diabetic retinopathy association was significant were CCT in diabetic patients with no retinal changes was 563.96 Std deviation (18.85) and in diabetic patients with retinopathy was 670.45 Std deviation (717.2) and P value = 0.004 (significant). There was significant correlation between increased corneal thickness and intraocular pressure were p-value = 0.002. Conclusions. We found that the central cornea of diabetic patients is thicker when compared with non-diabetic patients. Thicker central cornea associated with diabetes mellitus should be taken into consideration while obtaining accurate intraocular pressure measurements in diabetics.
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2型糖尿病患者角膜厚度和眼压的变化
目标本文的目的是报道伴有或不伴有视网膜病变的糖尿病患者的角膜中央厚度和眼压测量结果,并与非糖尿病对照组的结果进行比较。方法。共152例患者,152只眼。研究组分为3组:非糖尿病患者50例(对照组)。2型糖尿病50例,无糖尿病视网膜病变。伴有糖尿病视网膜病变的2型糖尿病患者52例。通过相关分析评估各组中糖化血红蛋白水平与眼压和视网膜变化之间的关系。结果。研究组与对照组人口学特征相似(P>0.05)。对照组平均CCT为553.62,标准差为14.47,糖尿病组平均CCT为622.27,标准差为507.09,均高于对照组,但差异未达到应用数学意义(p值= > 0.05)。无视网膜病变的糖尿病患者CCT为563.96 Std deviation(18.85),有视网膜病变的糖尿病患者CCT为670.45 Std deviation (717.2), P值= 0.004 (P值有统计学意义)。角膜厚度增加与眼压有显著相关性,p值= 0.002。结论。我们发现糖尿病患者的中央角膜较非糖尿病患者厚。糖尿病患者在获得准确的眼压测量时,应考虑与糖尿病相关的较厚的中央角膜。
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