{"title":"Continuous paramagnetophoretic microseparator for blood cells","authors":"Ki-Ho Han, J. Landers, A. B. Frazier","doi":"10.1109/SENSOR.2003.1216994","DOIUrl":null,"url":null,"abstract":"This paper presents a continuous paramagnetophoretic (PMP) microseparator for directly separating blood cells from whole blood by using a high gradient magnetic separation (HGMS) method. For high magnetic separation force, the present PMP separator is fabricated by microfabrication technology, and directly separates red and white blood cells from whole blood based on their magnetic properties. The theoretical model of the PMP microseparator is derived, and simulated values are compared with calculated values. A quantitative analysis using a hemocytometer shows that 92% of red blood cells are separated from whole blood by the present PMP microseparator.","PeriodicalId":196104,"journal":{"name":"TRANSDUCERS '03. 12th International Conference on Solid-State Sensors, Actuators and Microsystems. Digest of Technical Papers (Cat. No.03TH8664)","volume":"24 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2003-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"TRANSDUCERS '03. 12th International Conference on Solid-State Sensors, Actuators and Microsystems. Digest of Technical Papers (Cat. No.03TH8664)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/SENSOR.2003.1216994","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6
Abstract
This paper presents a continuous paramagnetophoretic (PMP) microseparator for directly separating blood cells from whole blood by using a high gradient magnetic separation (HGMS) method. For high magnetic separation force, the present PMP separator is fabricated by microfabrication technology, and directly separates red and white blood cells from whole blood based on their magnetic properties. The theoretical model of the PMP microseparator is derived, and simulated values are compared with calculated values. A quantitative analysis using a hemocytometer shows that 92% of red blood cells are separated from whole blood by the present PMP microseparator.
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