Gallium Containing Glass Polyalkenoate Bone Cements: Ion Release and E. coli Inhibition

L. Placek, A. Wren, A. Coughlan, M. Towler
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Abstract

The Glass Polyalkenoate Cement (GPC) series (LCon., LGa-1 and LGa-2) containing gallium (Ga) and a 50 wt% addition of E11 polyacrylic acid (PAA), previously developed, was evaluated for ion release, specifically Si, Ca, Zn and Ga, and E. coli inhibition. The maximum inhibition was observed in the t = 0 samples and was 0.35 mm for LCon. and 0.65 mm for LGa-1 and LGa-2.
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含镓玻璃聚烯酸盐骨水泥:离子释放和大肠杆菌抑制
玻璃聚烯烃水泥(GPC)系列(LCon)。我们评估了先前开发的含有镓(Ga)的LGa-1和LGa-2 (LGa-1和LGa-2)和添加50 wt%的E11聚丙烯酸(PAA)的离子释放,特别是Si, Ca, Zn和Ga,以及大肠杆菌的抑制作用。在t = 0样品中观察到最大的抑制作用,LCon为0.35 mm。LGa-1和LGa-2为0.65 mm。
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