The NanoCytometer: Screening Cells Based on Cell Size

A. Carbonaro, L. Godley, L. Sohn
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Abstract

Determination of cell size is crucial in many biomedical applications. Here, we show how resistive-pulse sensing and artificial pores can be used to detect and measure cell size accurately. Cell size is determined by measuring the change in resistance when an individual cell passes through the pore. As a proof-of-principle, we show that we are able to measure the change in size when cells undergo apoptosis
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纳米细胞计:基于细胞大小筛选细胞
细胞大小的测定在许多生物医学应用中是至关重要的。在这里,我们展示了如何使用电阻脉冲传感和人工孔隙来准确地检测和测量细胞大小。细胞的大小是通过测量单个细胞通过孔时阻力的变化来确定的。作为一个原理证明,我们表明我们能够测量细胞凋亡时大小的变化
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