MicroRNAs and Microcystins Induce Immune Disorders

Huiying Zhang, Daojun Chen
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Abstract

: Background: Cyanobacterial blooms caused by eutrophication can not only worsen the water environment, but also produce cyanobacterial toxins when some toxic cyanobacterial blooms proliferate. Microcystin is one of the most abundant cyanobacterial toxins found in reservoirs worldwide. Among its isomer, microcystin-leucine-arginine (MC-LR) is the most abundant and most toxic variety. Various experiments have clearly shown that MC-LR has hepatotoxicity and carcinogenicity, but there are relatively few studies on its immune damage effect. Numerous studies have shown that
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微rna和微囊藻毒素诱导免疫紊乱
背景:富营养化引起的蓝藻华不仅会恶化水环境,而且当一些有毒的蓝藻华繁殖时,还会产生蓝藻毒素。微囊藻毒素是在水库中发现的最丰富的蓝藻毒素之一。在其同分异构体中,微胱氨酸-亮氨酸-精氨酸(MC-LR)含量最多,毒性最强。各种实验明确表明MC-LR具有肝毒性和致癌性,但对其免疫损伤作用的研究相对较少。大量研究表明
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