Prevalence of neonatal sepsis and associated factors amongst neonates admitted in arbaminch general hospital, arbaminch, southern Ethiopia, 2019

Abdurhaman Mustefa, Amarch Abera, Asegedech Aseffa, Tsigereda Abathun, Nega, Degefa, H. Tadesse, Tomas Yeheyis
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引用次数: 16

Abstract

Background: There are an estimated 2.9 million deaths worldwide from sepsis every year (44% of them in children under 5 years of age) and one quarter of these are due to neonatal sepsis. According to global burden of neonatal sepsis about 6.9 million neonates were diagnosed with possible serious bacterial infection needing treatment from these 2.9 million cases of neonates needing treatment occur in sub-Saharan Africa. Method: An institution based cross sectional study with retrospective document review was conducted among neonates admitted to neonatal intensive care unit from December 2017 to December 2018 in arbaminch general hospital. Sample size was calculated by using single population proportion sample formula with a final sample size of 351. Data were collected a checklist. Using SPSS version 21 Binary and multiple logistic regressions have been used to observe the association between independent variables and dependent variable. Result: The magnitude of neonatal sepsis was 78.3%. APGAR<6,PROM> 18 hours and duration of labour>12 hours were positively associated with neonatal sepsis where as gestational age > 37 weeks and birth weight >2500 grams were protective factors as evidenced by statistical result of 2.33(0.205-0.33), 1.32(0.71-0.84), 1.20(0.70-0.95), 0.85(0.34-0.815) and 0.12(0.04-030) respectively. Conclusion and recommendation: The finding of this study shows that neonatal sepsis accounts the highest proportion cases amongst neonates admitted in the hospital. Gestational age, birth weight, APGAR score, PROM and duration of labour were found to be determinants of neonatal sepsis. Therefore, service utilization of mothers, early detection of risky situations and appropriate practice of newborn care can halt the problem.
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2019年埃塞俄比亚南部arbaminch arbaminch综合医院新生儿脓毒症患病率及相关因素
背景:据估计,全世界每年有290万人死于败血症(其中44%为5岁以下儿童),其中四分之一是新生儿败血症。根据全球新生儿败血症负担,约690万新生儿被诊断为可能的严重细菌感染,需要治疗,其中290万例需要治疗的新生儿发生在撒哈拉以南非洲。方法:对2017年12月至2018年12月在阿巴因奇综合医院新生儿重症监护病房住院的新生儿进行回顾性研究。样本量采用单总体比例样本公式计算,最终样本量为351。数据收集清单。使用SPSS version 21二元和多元逻辑回归来观察自变量和因变量之间的关联。结果:新生儿败血症发生率为78.3%。APGAR 18小时、产程>12小时与新生儿脓毒症呈正相关,其中胎龄> 37周、出生体重>2500克是新生儿脓毒症的保护因素,统计结果分别为2.33(0.205 ~ 0.33)、1.32(0.71 ~ 0.84)、1.20(0.70 ~ 0.95)、0.85(0.34 ~ 0.815)、0.12(0.04 ~ 030)。结论和建议:本研究的发现表明,新生儿败血症占入院新生儿的比例最高。发现胎龄、出生体重、APGAR评分、胎膜早破和分娩时间是新生儿脓毒症的决定因素。因此,母亲的服务利用,早期发现危险情况和适当的新生儿护理做法可以制止这一问题。
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