A Prospective Randomised Study Of Combination Of Epidural Bupivacaine With Clonidine And Bupivacaine For Postoperative Analgesia

Abstract

After obtaining institutional ethical committee approval and written informed consent, 90 adult patients, ages 30-75 yrs, of either gender belonging to ASA physical status 1 and 2 scheduled for abdominal, obstetrical, gynecological and orthopedic surgery under epidural anaesthesia, during the study period (Jan 2009 Dec 2009) were recruited. Patients for whom central neuraxial block was contraindicated and those with history of poorly controlled hypertension, angina, congestive cardiac failure, atrial fibrillation, arrhythmias, weight >95kg, age >75years, ASA grade 3 and 4, on tricyclic anti-depressants, alpha-2 adrenergic agonists or opioids were excluded from this study.