CONTACT DERMATITIS SECONDARY TO PHENYLEPHRINE EYE DROP: A CASE REPORT

Sunanda Biradar, Kartik Nuchhi, A. Kulkarni, Shivanand I. Lubadude, Kirankumar Awati, S. Badiger, R. Kattimani, Santosh R. Awasthi
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Abstract

Phenylephrine, a sympathomimetic drug, is commonly used in eye examinations to dilate the pupil of the eye and to differentiate scleritis from episcleritis. It is extensively used as a mydriatic agent by ophthalmologists and may cause allergic contact reactions even though it is rare. Here is a case of 46 years old female patient with acute-onset edema and erythema of both eyes associated with watering, a burning sensation, and moderate discomfort characterized by contact dermatitis. The patient develops adverse drug reaction to an eye drop containing Tropicamide 0.8%w/v + Phenylephrine 5%w/v used prior to eye fundus examination. Although uncommon, cases of allergic reaction to Phenylephrine cannot be ruled out, hence it is advisable to all the clinicians/Ophthalmologist to encourage and conduct the sensitivity test for Phenylephrine allergy, in order to minimize the possible adverse effects and ruinous consequences.
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苯肾上腺素滴眼液继发接触性皮炎1例
苯肾上腺素是一种拟交感神经药物,常用于眼科检查,以扩大瞳孔和区分巩膜炎和外巩膜炎。它被眼科医生广泛用作抗炎剂,即使它很罕见,也可能引起过敏接触反应。这里有一个46岁的女性患者,她的双眼急性水肿和红斑,伴有流泪,灼烧感和中度不适,其特征是接触性皮炎。患者在眼底检查前使用含Tropicamide 0.8%w/v + Phenylephrine 5%w/v的滴眼液,出现药物不良反应。虽然不常见,但不能排除对苯肾上腺素过敏的病例,因此建议所有临床医生/眼科医生鼓励并进行苯肾上腺素过敏敏感性试验,以尽量减少可能出现的不良反应和破坏性后果。
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