Preparing, Exploring and Comparing Cancer Simulation Results within a Large Parameter Space

Abstract

The ACGT Oncosimulator is an integrated Grid-based system, under development within a 25-partner European-Japanese project, for patient-specific simulation of the response of a tumour and surrounding tissue to various forms of therapy. The validation of the simulation code is an activity requiring extensive human-driven visual investigation of the influence of each of the dozens of parameters to the code, and comparison of the simulation results against the known outcomes of past patient treatments. This activity therefore calls for a visualisation environment that supports users in working with an extremely large potential result space, and in rapidly setting up visualisations that highlight the differences between chosen subsets of available results. We describe the innovative features of the OncoRecipeSheet, an environment designed to meet these requirements.