[Non-surgical treatment of the sleep related breathing disorders in adults].

C. Philippe
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Abstract

The treatment of obstructive sleep apnoea/hypopnoea syndrome (OSAHS) must allow for the suppression of symptoms and also prevent its immediate and long-term consequences. The evaluation of the effectiveness of treatments is now based on a normal apnea/hypopnea index, a normal oxygen saturation and the disappearance of sleep fragmentation. Clinical and biological follow-up of co-morbidities must be ensured. Compliance with treatment, a major element of success, must be monitored. Continuous Positive Airway Pressure (CPAP) is still the most effective and widely used treatment. However, mandibular advancement orthosis is now recommended as a first-line treatment in moderate forms in the absence of severe cardiovascular comorbidities (CV) and remains a therapeutic alternative in the event of refusal or intolerance to CPAP. Nutritional management in cases of obesity and a physical activity program must be systematically offered. A reduction in nocturnal breathing disorders can also be achieved by using a device in the event of positional OSAHS, or by limiting fluid movements. The contribution of myofunctional therapy is currently being evaluated. Very recently, a study testing the efficiency of pharmacological treatment on the severity of OSAHS and the reactivity of geniogloss appears to be promising. The evaluation of these different treatments and their combination should make it possible to evolve towards a personalised management adapted to each patient.
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成人睡眠相关呼吸障碍的非手术治疗
对阻塞性睡眠呼吸暂停/低通气综合征(OSAHS)的治疗必须考虑到对症状的抑制,并防止其直接和长期后果。治疗效果的评估现在是基于正常的呼吸暂停/低呼吸指数,正常的氧饱和度和睡眠碎片的消失。必须确保对合并症进行临床和生物学随访。治疗的依从性是成功的一个主要因素,必须加以监测。持续气道正压通气(CPAP)仍然是最有效和广泛使用的治疗方法。然而,在没有严重心血管合并症(CV)的情况下,下颌推进矫形器现在被推荐为中等形式的一线治疗,并且在拒绝或不耐受CPAP的情况下仍然是一种治疗选择。在肥胖的情况下,营养管理和体育活动计划必须系统地提供。在体位性OSAHS的情况下,也可以通过使用装置或限制液体运动来减少夜间呼吸障碍。肌功能治疗的作用目前正在评估中。最近,一项研究测试了药物治疗对OSAHS严重程度的有效性和genogloss的反应性,似乎很有希望。对这些不同的治疗方法及其组合进行评估,应该使其有可能朝着适合每位患者的个性化管理发展。
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[Agenesis]. [What prospects for the sleep apnea syndrome and connected health?] [In Memoriam, Professor Christian Guilleminault]. [Orthodontic management of obstructive sleep-disordered respiratory disorders]. [Physiopathology of obstructive sleep apnea syndrome].
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