Pengaruh Variasi Konsentrasi Ekstrak Buah Mahkota Dewa (Phaleria macrocarpa) Terhadap Stabilitas Fisik Sediaan Krim

Nur Ain Thomas, Robert Tungadi, Yuni Sarah Manoppo
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引用次数: 1

Abstract

God's crown is one of the plants with various components with flavonoid as one of these components, which is an abundant plant metabolite component in nature that significantly functions for the plant's growth and antioxidants. This study aimed to examine The Concentration Variation Effect of 70% Ethanol Extract from God's Crown (Phaleria Macrocarpa) Towards The Physical Stability of Cream Preparations by variating the extract concentration. The formula concentration on the extract consists of FI (1%), FII (3%), FIII (5%), by stearic acid, paraffin liquid, alcohol cetyl, paraben propyl for the oil phase, aquadest, triethanolamine (TEA), and methylparaben for the water phase. Further evaluations include organoleptic test (smell, color, texture), pH test, homogeneity test, viscosity test, distribution test, and adhesion test. Each evaluation result found changes as intended by the research purpose, which is the effect of the extract's concentration variation on the physical stability of the cream preparations.
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神的王冠提取物(phaller macrocarpa)的浓度变化对克里米亚人的身体稳定性的影响
神冠是植物中含有多种成分的植物之一,类黄酮是其中一种成分,是自然界中丰富的植物代谢物成分,对植物的生长和抗氧化有重要作用。本研究旨在考察70%乙醇提取物浓度变化对药膏制剂物理稳定性的影响。萃取物的配方浓度为:FI(1%)、FII(3%)、FIII(5%),由硬脂酸、石蜡液、十六烷基醇、对羟基苯甲酸丙基(油相)、aquadest、三乙醇胺(TEA)和对羟基苯甲酸甲酯(水相)组成。进一步的评估包括感官测试(气味、颜色、质地)、pH值测试、均匀性测试、粘度测试、分布测试和附着力测试。每个评价结果都发现了研究目的预期的变化,即提取物浓度变化对乳膏制剂物理稳定性的影响。
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