{"title":"An Efficient Approach to Detect a Protein Community from a Seed","authors":"D. Wu, Xiaohua Hu","doi":"10.1109/CIBCB.2005.1594909","DOIUrl":null,"url":null,"abstract":"Community structure is a topological property common to many networks. We present in this paper an efficient and accurate approach to detecting a community in a protein-protein interaction network from a given seed protein. Our experimental results show strong structural and functional relationships among member proteins within each of the communities identified by our approach, as verified by MIPS complex catalogue database and annotations.","PeriodicalId":330810,"journal":{"name":"2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology","volume":"21 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"24","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2005 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/CIBCB.2005.1594909","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 24
Abstract
Community structure is a topological property common to many networks. We present in this paper an efficient and accurate approach to detecting a community in a protein-protein interaction network from a given seed protein. Our experimental results show strong structural and functional relationships among member proteins within each of the communities identified by our approach, as verified by MIPS complex catalogue database and annotations.
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