{"title":"Metabolic Pathways and Engineering of Polyhydroxyalkanoate Biosynthesis","authors":"K. Taguchi, S. Taguchi, K. Sudesh, A. Maehara, Takeharu Tsuge, Y. Doi","doi":"10.1002/3527600035.BPOL3A07","DOIUrl":null,"url":null,"abstract":"Introduction \nMetabolic Pathways for PHA Biosynthesis \nOrganization of the Genes Involved in PHA Biosynthesis \nMonomer-supplying Enzymes for PHA Biosynthesis \nβ-Ketothiolase (PhaA) \nAcetoacetyl-CoA Reductase (PhaB) \n(R)-3-Hydroxyacyl-ACP–CoA transferase (PhaG) \n(R)-Specific Enoyl-CoA Hydratase (PhaJ) \n \n \nMetabolic Engineering and Improvements in PHA Biosynthesis \nMetabolic Engineering for PHA Production in Recombinant Escherichia coli \nMetabolic Improvement for PHA Production in Ralstonia eutropha PHB-4 and Pseudomonads \n \n \nOutlook and Perspectives \n \n \nKeywords: \n \nmetabolic pathway; \nmetabolic engineering; \nmetabolic improvement; \npolyhydroxyalkanoates; \nPHA; \nbiosynthesis; \nacetyl-CoA dimerization step; \nfatty acid metabolism; \nde novo fatty acid biosynthesis; \nβ-oxidation; \nrecombinant; \nPHA synthesis genes; \nphaA; \nphaB; \nphaC; \nphaG; \nphaJ","PeriodicalId":165163,"journal":{"name":"Biopolymers Online","volume":"13 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2002-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"9","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biopolymers Online","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/3527600035.BPOL3A07","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 9
聚羟基烷酸酯生物合成的代谢途径与工程
介绍PHA生物合成代谢途径PHA生物合成相关基因的组织PHA生物合成单体供应酶β-酮硫酶(PhaA)乙酰乙酰辅酶a还原酶(PhaB) (R)-3-羟基酰基acp -辅酶a转移酶(PhaG) (R)-特异性烯酰辅酶a水合酶(PhaJ) PHA生物合成代谢工程及改进重组大肠杆菌生产PHA的代谢工程富营养化Ralstonia PHB-4生产PHA的代谢改进关键词:代谢途径;代谢工程;代谢改善;polyhydroxyalkanoates;PHA;生物合成;乙酰辅酶a二聚化步骤;脂肪酸代谢;从头脂肪酸生物合成;β氧化;重组;PHA合成基因;phaA;伤健;phaC;phaG;phaJ
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