Intravenous Levetiracetam in Refractory Status Epilepticus

P. Bhargava
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引用次数: 3

Abstract

Refractory status epilepticus is defined as seizures, which last longer than 60 minutes despite treatment with a benzodiazepine and an adequate loading dose of intravenous antiepileptic drug. 1It has a high mortality and requires prompt management. Currently available drugs like midazolam, pentobarbitol and propofol can cause hypotension and respiratory depression. We present control of Refractory status in three critically ill patients using intravenous levetiracetam, which has a unique drug profile.
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静脉注射左乙拉西坦治疗难治性癫痫持续状态
难治性癫痫持续状态定义为癫痫发作,尽管使用苯二氮卓类药物和足够负荷剂量的静脉注射抗癫痫药物治疗,但持续时间超过60分钟。该病死亡率高,需要及时治疗。目前可用的药物如咪达唑仑、戊巴比醇和异丙酚可引起低血压和呼吸抑制。我们提出控制难治性状态在三个危重病人静脉注射左乙拉西坦,它有一个独特的药物配置文件。
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