Portable Analytical Device for Bedside Monitoring of the Functional State of the Hemostasis System

D. Slizevich, E. Zhukov, Fedor Gubarev
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Abstract

The paper considers the issues of practical implementation of the portable analytical device for bedside monitoring of the functional state of the hemostasis system using whole blood. The design of devices for evaluating the functioning of the hemostasis system based on whole blood analysis is a promising area of research and development in the field of medical technology, as it can significantly reduce the time of one test. The block diagram of the device, basic solutions for hardware and software components, as well as the layout of the device are considered. Various designs of disposable blood sampling cuvettes are presented, and the choice of a cuvette for a commercial device is discussed. The device was used to assess vascular-platelet hemostasis of volunteers in real time. The results obtained demonstrated a high degree of correlation with the standard method used to assess the system of regulation of the aggregate state of blood in clinical practice. The main advantage of the developed system is the possibility of studying whole blood in the Point-of-Care Test mode (at the patient's bedside).
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床边监测止血系统功能状态的便携式分析装置
本文讨论了床边监测全血止血系统功能状态的便携式分析装置的实际实施问题。基于全血分析的止血系统功能评估装置的设计是医疗技术领域一个很有前途的研究和发展领域,因为它可以显著减少一次测试的时间。考虑了器件的框图、硬件和软件组件的基本解决方案以及器件的布局。介绍了各种设计的一次性血液取样比色皿,并讨论了商业设备比色皿的选择。该装置用于实时评估志愿者血管血小板止血情况。所获得的结果证明了与用于评估临床实践中血液聚集状态调节系统的标准方法的高度相关性。开发的系统的主要优点是可以在护理点测试模式下(在患者床边)研究全血。
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