Affinity of liver cells to Sudanophilia and PAS in castrated treated mice

Abstract

The present study was conducted on seventy five healthy males of Swiss albino mice, which were divided into 5 groups (N=15 mice per each group). The first group were intact (control); the second one were castrated; the third group were castrated treated with 50µg/ kg testosterone; the forth one were castrated treated with 10µl/g. grape juice, and the fifth one were intact treated with 3mg/kg F. hormonis. The frozen sections ofmice liver tissue from both castrated and intact treated subjects with 3mg/kg Ferula hormonis showed a strong affinity to sudanophilia (+++) as compared with the intact (control) group. Whereas frozen sections from castrated subjects treated with 50µg/kg of testosterone or with10µl/g of grape juice showed a moderate affinity to sudanophilia (++) as compared with the control. The histological sections of liver tissue from castrated group or intact treated with 3mk/kg F. hormonis revealed a decrease in glycogen contents as compared with the control group. On the other hand, sections from castrated subjects treated with 50µg/kg of testosterone or with 10µl/g of grape juice appeared normal appearance to intact (control) subjects.