Blood pressure — Heart rate syncronization coefficient as a complementary indicator of baroreflex mechanism efficiency

2015 XVIII International Conference on Soft Computing and Measurements (SCM) Pub Date : 2015-05-19 DOI:10.1109/SCM.2015.7190446

M. Bogachev, O. Markelov, N. Pyko, S. A. Pyko

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引用次数: 7

Abstract

We aimed at studying the efficiency of blood pressure - heart rate feedback regulation, in particular the arterial baroreflex mechanism. We analyzed 150 short-term beat-to-beat recordings of blood pressure and pulse intervals and calculated their level of synchronization. We determined the synchronization coefficient as a fraction of the record fragments where the standard deviation of the Hilbert phase difference of blood pressure and pulse intervals was below a given threshold. Our results indicate that the synchronization coefficient is significantly lower in records with high blood pressure variability while does not correlate significantly with the arterial baroreflex sensitivity. Accordingly, the synchronization coefficient may be used as a complementary indicator of blood pressure feedback regulation, since it reflects how often the feedback mechanism is activated. We suggest that the product of the synchronization coefficient and the baroreflex sensitivity could be used as a potential measure of the total efficiency of baroreflex mechanism and thus of blood pressure feedback control.

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血压-心率同步系数作为压反射机制效率的补充指标

我们旨在研究血压-心率反馈调节的效率，特别是动脉压力反射机制。我们分析了150次短期搏动记录的血压和脉搏间隔，并计算了它们的同步水平。我们将同步系数确定为血压和脉搏间隔的希尔伯特相位差的标准偏差低于给定阈值的记录片段的一部分。我们的研究结果表明，同步系数在高血压变异性的记录中显着降低，而与动脉压力反射敏感性没有显着相关。因此，同步系数可以作为血压反馈调节的补充指标，因为它反映了反馈机制被激活的频率。我们认为，同步系数和压反射灵敏度的乘积可以作为压反射机制总效率的潜在衡量标准，从而可以衡量血压反馈控制的效率。

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2015 XVIII International Conference on Soft Computing and Measurements (SCM)

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