Factors Associated with Accelerated Progression of Chronic Kidney Disease in Patients from the Colombian Caribbean Coast

Angela J. Pereira-Morales, Walberto Buelvas, Víctor De la Espriella, Albert Montenegro, Luis H. Rojas, W. Amador
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Abstract

Background: Chronic Kidney Disease (CKD) is a global public health problem with increasing prevalence and a substantial burden on healthcare systems. The characteristics of rapid progressors and factors that may predict accelerated CKD progression require further exploration, especially since there are no published studies about this topic in Colombia. Purpose: To identify the clinical and sociodemographic factors associated with the rapid progression of CKD in a large cohort of Colombian patients. Methods: This retrospective observational study included two cohorts of G1 to G4 stage CKD patients without dialysis from the Colombian North Coast. Follow-up was conducted for 18 months (n=14,420) and 24 months (n=10,042). Patients were divided into rapid progressors and stable progressors based on the glomerular filtration rate (GFR) slope
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哥伦比亚加勒比海沿岸患者慢性肾病加速进展的相关因素
背景:慢性肾脏疾病(CKD)是一个全球性的公共卫生问题,发病率不断上升,给卫生保健系统带来了沉重的负担。快速进展者的特征和可能预测CKD加速进展的因素需要进一步探索,特别是在哥伦比亚还没有发表关于这一主题的研究。目的:在一大批哥伦比亚患者中确定与CKD快速进展相关的临床和社会人口学因素。方法:这项回顾性观察性研究包括两组来自哥伦比亚北海岸的G1至G4期未透析的CKD患者。随访18个月(n=14,420)和24个月(n=10,042)。根据肾小球滤过率(GFR)斜率
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