Hypoglycemic Effect of Olive Oil (Olea europea) on Alloxan- Induced Diabetic Albino Rats.

Abstract

This research work is aimed  at  investigating the hypoglycemic effect  of  olive oil obtained from the seeds  of olive tree (Olea  europea,)  on alloxan-induced diabetic Albino rats. The results obtained show that olive oil  (Olea europea) exhibit   hypoglycemic effect on alloxan-induced diabetic Albino rats with the lower  dose (150mg/kg/b.wt).  as the most effective dose for the significant treatment of type 1 diabetes.  Medium and  High  doses  however showed  an  insignificant  effect  compared  to the control  groups. When the, standard drug (positive control) 60 mg/kg/b.wt  was  administered to the rats , the glucose level of the group 2 alloxan-induced diabetic rats decreased gradually to the range between the normal range 4.9-5.5 mg/dl according to the world health standard (W.H.O, 2014). During treatment, the body weight  of  the rats was  observed to increase  as  the  rats responded  to  the  hypoglycemic effect of the oil treatment. As the treatment continues, the   rats  look  healthier  which  shows  a  positive  response   to  the  olive  oil  treatment.