M. Shvedsky, V. Bychkov, V. V. Matvienko, O.G. Solovyova, R. I. Duboshinsky, D.A. Vagina
{"title":"On the question of carcinogenesis in superinvasive opisthorchiasis","authors":"M. Shvedsky, V. Bychkov, V. V. Matvienko, O.G. Solovyova, R. I. Duboshinsky, D.A. Vagina","doi":"10.34014/mpphe.2021-226-229","DOIUrl":null,"url":null,"abstract":"Retrospective analysis of foreign literature present in PubMed was carried out with the purpose to define possible influence of superinvasive opisthorchiasis on possible development of cholangiocellular carcinoma. After the research we conclude that O. Felineus doesn’t have an entry point during the initiation stage of carcinogenesis but rather acts as a promotor of cholangiocarcinoma (СС), and therefore cannot be considered a primary cause of the disease without additional influence of another carcinogens and specific factors that increase the probability of cholangiocarcinoma development (chronic inflammation, free radicals). \nKeywords: superinvasive opisthorchiasis, parasitism, immune system, carcinogenesis.","PeriodicalId":378573,"journal":{"name":"Materialy VIII Vserossijskoj konferencii s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka»","volume":"46 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materialy VIII Vserossijskoj konferencii s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka»","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34014/mpphe.2021-226-229","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Retrospective analysis of foreign literature present in PubMed was carried out with the purpose to define possible influence of superinvasive opisthorchiasis on possible development of cholangiocellular carcinoma. After the research we conclude that O. Felineus doesn’t have an entry point during the initiation stage of carcinogenesis but rather acts as a promotor of cholangiocarcinoma (СС), and therefore cannot be considered a primary cause of the disease without additional influence of another carcinogens and specific factors that increase the probability of cholangiocarcinoma development (chronic inflammation, free radicals).
Keywords: superinvasive opisthorchiasis, parasitism, immune system, carcinogenesis.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
