Assessment of the role of lipoprotein a level in the development of cardiovascular diseases

Vishneva E, Vishneva K
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Abstract

A comparative trial within 2 groups of patients with cardiovascular diseases who have high and normal levels of lipoprotein (a) was conducted to determine the link between high levels of Lp (a) and the nature of the development of cardiovascular events. According to the results of the study, conclusions about the significance of the level of Lp(a), as well as hypolipidemic therapy in patients with cardiovascular pathology were made. The features of the population of patients with an expected increase in Lp(a) and the predominance of lesions of the brachiocephalic arteries among individuals with increased Lp(a) were revealed. Hypolipidemic statin therapy with a passable correction of the lipid spectrum does not always allow to control the increase in Lp(a)
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脂蛋白a水平在心血管疾病发展中的作用评估
在两组脂蛋白(A)水平高和正常的心血管疾病患者中进行了一项比较试验,以确定脂蛋白(A)水平高与心血管事件发展的性质之间的联系。根据研究结果,得出脂蛋白(a)水平在心血管病变患者中的意义及低血脂治疗的结论。揭示了预期Lp(a)增加的患者群体的特征以及Lp(a)增加的个体中头臂动脉病变的优势。降血脂的他汀类药物治疗与脂质谱的适当校正并不总是允许控制Lp的增加(a)。
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